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Our Mission

Create awareness
strengthen capacity and power innovations to make Bangladesh a global leader in the field of biomedical sciences and translational research
Innovate
Provide solutions to public health problems through translation of innovative ideas into technologies
Pioneering research in genetic disorders
Accelerate studies on genetic disorders in Bangladesh and training of biomedical scientists and clinicians in laboratory based research utilizing immunological and molecular biological tools

INSIDE IDESHI

Like glucose-6-phosphate dehydrogenase (G6PD) deficient hemizygous males and homozygous females, heterozygous females could also manifest hemolytic crisis, neonatal hyperbilirubinemia or kernicterus upon exposure to oxidative stress induced by certain foods such as fava beans, drugs or infections. Although hemizygous males and homozygous females are easily detected by conventional G6PD enzyme assay method, the heterozygous state could be missed by the conventional methods as the mosaic population of both normal and deficient RBCs circulates in the blood.... READ MORE

Bangladesh lies in the global thalassemia belt, which has a defined mutational hot-spot in the beta-globin gene. The high carrier frequencies of beta-thalassemia trait and hemoglobin E-trait in Bangladesh necessitate a reliable DNA-based carrier screening approach that could supplement the use of hematological and electrophoretic indices to overcome the barriers of carrier screening....READ MORE

Beta-thalassemia, an inherited hemoglobinopathy caused by beta-globin gene mutations and deregulation of the synthesis of the β-globin chain, is one of the most common autosomal recessive disorders worldwide. Approximately 65,000–70,000 babies are born each year with different types of thalassemia, most of whom are affected by beta-thalassemia major (BTM), the most severe form of the disorder. In beta-thalassemia, pathophysiology caused by an imbalance in the ratio of alpha globin chains to beta globin chains, and the presence of excess alpha-globin chain in red blood cells (RBCs), results in oxidative damage to RBCs....READ MORE

Acute respiratory infections (ARIs), in particular, pneumonia, remain the persistent and pervasive deterrent to public health. It is responsible for substantial morbidity and mortality worldwide, especially in children <5 years of age. But the death rate due to ARI is mostly concentrated in .... READ MORE

Glucose-6-phosphate dehydrogenase (G6PD) deficiency is a common X-linked human enzyme defect of red blood cells (RBCs). Individuals with this gene defect appear normal until exposed to oxidative stress which induces hemolysis. Consumption of certain foods such as fava beans, legumes; infection with bacteria or virus; and use of certain drugs....READ MORE

Atypical manifestation of Huntington's disease (HD) could inform ongoing research into HD genetic modifiers not present in the primarily European populations studied to date. This work demonstrates that expanding HD genetic testing into under‐resourced healthcare settings can benefit both local communities and ongoing research into HD etiology and new therapies....READ MORE

MEET OUR LEADERSHIP

Passionately committed to serve as a hub for enabling research and training activities in Bangladesh

Dr. Firdausi Qadri

Chairperson

Dr. Firdausi Qadri, an international scientist at the Centre for Vaccine Sciences in International Centre for Diarrheal Disease Research, Bangladesh (icddr,b), has been working in collaboration with international... READ MORE

Dr. Syed Saleheen Qadri

Scientific Coordinator

Dr. Md Kaiissar Mannoor

Senior Scientist and Head

Dr. Kaiissar Mannoor is a cellular and molecular biologist with a long-standing interest in protective immune responses to infectious diseases with special emphasis on malaria and diarrheal pathogens... READ MORE

CONTACT US

Institute of Public Health Building,

2nd Floor, Mohakhali,

Dhaka 1212, Bangladesh

info@ideshi.org >

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